Plasma-assisted crystallization

Cold plasma system for crystallization control and automation.

PlaSeed is a spin-off company from CentraleSupélec (Paris-Saclay University) which develops, manufactures and sells cold plasma technologies for crystallization control.

Request a demonstration See how it works ↓
Technology

Cold plasma makes crystallization simpler and faster

Cold plasma is a non-equilibrium ionized gas that efficiently triggers crystal nucleation in solution. We provide a cold plasma probe that delivers low-energy plasma bubbles to the solution, and software that automates crystallization process development.

Cold plasma discharge triggering nucleation at the tip of a PlaSeed probe, immersed in solution.
Advantages

Easy to handle. Easy to automate.

Zero preparation

Only need N2 gas and power supplies.

Continuous cycles

Crystallization cyles can run autonomously 24/7.

R&D time saved

Less time lost on logistics, more time for analysis and decision-making.

Traceability

Data from each crystallization cycle are stored in a dedicated folder, and exported in a final report.

How it works

Software-driven workflow

The software guides you step-by-step from the configuration of the probe to the export of the report containing the data.

01

Probe configuration

The probe is configured to generate low-energy cold plasma bubbles within the crystallization reactor. Manual testing available.

02

Automation

The software connects to open-platform equipment (Huber, Julabo, SOPAT,...), loads your experimental plan, and runs the scheduled crystallization cycles autonomously.

03

Report generation

Data from each crystallization can be loaded, plotted and exported in a report.

The PlaSeed automation software main menu: Probe Control, PAT Tools, Post analysis, and Automation modules.

Application domain

Built for chemical & pharma R&D

"As a non-intrusive seeding technique, plasma-induced nucleation has several advantages over conventional seeding methods used in the pharmaceutical industry."

Olivier Monnier, Former Head of Crystallization & Physical Quality Group, Sanofi R&D

Formulation development Particle engineering Chemical & Pharma R&D

Team

Arthur Salmon Arthur SalmonCEO and founder
Christophe Laux Christophe LauxPlasma advisor
François Puel François PuelCrystallization advisor

Partners

Let's talk

Need to get in touch with us?

Tell us about your application — we'll get back to you to set up a demonstration.